Dissertation Mentor
Education & Training
- Bachelor of Science, Biochemistry, Southern Methodist University, Dallas, Tx.
Representative Publications
Sharma AX, Quittner-Strom EB, Lee Y, Johnson JA, Martin SA, Yu X, Li J, Lu J, Cai Z, Chen S, Wang MY, Zhang Y, Pearson MJ, Dorn AC, McDonald JG, Gordillo R, Yan H, Thai D, Wang ZV, Unger RH, Holland WL. Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice. Cell reports. 2018; 22(7): 1760-1773.
Shao M, Vishvanath L, Busbuso NC, Hepler C, Shan B, Sharma AX, Chen S, Yu X, An YA, Zhu Y, Holland WL, Gupta RK. De novo adipocyte differentiation from Pdgfrβ+ preadipocytes protects against pathologic visceral adipose expansion in obesity. Nature communications. 2018; 9(1): 890.
Sharma AX, Holland WL. Adiponectin and its Hydrolase-Activated Receptors. J Nat Sci. 2017; 3(6): e396.
Hepler C, Shao M, Xia JY, Ghaben AL, Pearson MJ, Vishvanath L, Sharma AX, Morley TS, Holland WL, Gupta RK. Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice. Elife. 2017; 6.
Holland WL, Xia JY, Johnson JA, Sun K, Pearson MJ, Sharma AX, Quittner-Strom E, Tippetts TS, Gordillo R, Scherer PE. Inducible overexpression of adiponectin receptors highlights the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis. Molecular metabolism. 2017; 6(3): 267-75.
Xia JY, Holland WL, Kusminski CM, Sun K, Sharma AX, Pearson MJ, Sifuentes AJ, McDonald JG, Gordillo R, Scherer PE. Targeted induction of ceramide degradation leads to improved systemic metabolism and reduced hepatic steatosis. Cell metabolism. 2015; 22(2): 266-78.